Recent publications

  1. Ogbonna, EN, Paul, A, Ross Terrell, J, Fang, Z, Chen, C, Poon, GMK, Boykin, DW, Wilson, WD. (2022) Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines. Bioorg Med Chem, 68:116861
  2. Schneider, AL, Albrecht, AV, Huang, K, Germann, MW, Poon, GMK. (2022) Self-Consistent Parameterization of DNA Residues for the Non-Polarizable AMBER Force Fields. Life (Basel), 12:
  3. Stark, B, Poon, GMK, Wyrick, JJ. (2021) CTCF puts a new twist on UV damage and repair in skin cancer. Mol Cell Oncol, 8:2009424
  4. Duan, M, Sivapragasam, S, Antony, JS, Ulibarri, J, Hinz, JM, Poon, GMK, Wyrick, JJ, Mao, P. (2022) High-resolution mapping demonstrates inhibition of DNA excision repair by transcription factors. Elife, 11:
  5. Sivapragasam, S, Stark, B, Albrecht, AV, Bohm, KA, Mao, P, Emehiser, RG, Roberts, SA, Hrdlicka, PJ, Poon, GMK, Wyrick, JJ. (2021) CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma. EMBO J, 40:e107795
  6. Vo, TD, Schneider, AL, Poon, GMK, Wilson, WD. (2021) DNA-facilitated target search by nucleoproteins: Extension of a biosensor-surface plasmon resonance method. Anal Biochem, 629:114298
  7. Vo, TD, Schneider, AL, Wilson, WD, Poon, GMK. (2021) Salt bridge dynamics in protein/DNA recognition: a comparative analysis of Elk1 and ETV6. Phys Chem Chem Phys, 23:13490-13502
  8. Le Coz, C, Nguyen, DN, Su, C, Nolan, BE, Albrecht, AV, Xhani, S, Sun, D, Demaree, B, Pillarisetti, P, Khanna, C, Wright, F, Chen, PA, Yoon, S, Stiegler, AL, Maurer, K, Garifallou, JP, Rymaszewski, A, Kroft, SH, Olson, TS, Seif, AE, Wertheim, G, Grant, SFA, Vo, LT, Puck, JM, Sullivan, KE, Routes, JM, Zakharova, V, Shcherbina, A, Mukhina, A, Rudy, NL, Hurst, ACE, Atkinson, TP, Boggon, TJ, Hakonarson, H, Abate, AR, Hajjar, J, Nicholas, SK, Lupski, JR, Verbsky, J, Chinn, IK, Gonzalez, MV, Wells, AD, Marson, A, Poon, GMK, Romberg, N. (2021) Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients. J Exp Med, 218:
  9. Poon, GMK. (2022) The Non-continuum Nature of Eukaryotic Transcriptional Regulation. Adv Exp Med Biol, 1371:11-32
  10. Afek, A, Shi, H, Rangadurai, A, Sahay, H, Senitzki, A, Xhani, S, Fang, M, Salinas, R, Mielko, Z, Pufall, MA, Poon, GMK, Haran, TE, Schumacher, MA, Al-Hashimi, HM, Gordân, R. (2020) DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature, 587:291-296
  11. Ha, VLT, Erlitzki, N, Farahat, AA, Kumar, A, Boykin, DW, Poon, GMK. (2020) Dissecting Dynamic and Hydration Contributions to Sequence-Dependent DNA Minor Groove Recognition. Biophys J, 119:1402-1415
  12. Xhani, S, Lee, S, Kim, HM, Wang, S, Esaki, S, Ha, VLT, Khanezarrin, M, Fernandez, GL, Albrecht, AV, Aramini, JM, Germann, MW, Poon, GMK. (2020) Intrinsic disorder controls two functionally distinct dimers of the master transcription factor PU.1. Sci Adv, 6:eaay3178
  13. Liu, B, Bashkin, JK, Poon, GMK, Wang, S, Wang, S, Wilson, WD. (2019) Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions. Biochimie, 167:1-11
  14. Vo, T, Albrecht, AV, Wilson, WD, Poon, GMK. (2019) Quantifying length-dependent DNA end-binding by nucleoproteins. Biophys Chem, 251:106177
  15. Huang, K, Xhani, S, Albrecht, AV, Ha, VLT, Esaki, S, Poon, GMK. (2019) Mechanism of cognate sequence discrimination by the ETS-family transcription factor ETS-1. J Biol Chem, 294:9666-9678
  16. Wohlfahrt, T, Rauber, S, Uebe, S, Luber, M, Soare, A, Ekici, A, Weber, S, Matei, AE, Chen, CW, Maier, C, Karouzakis, E, Kiener, HP, Pachera, E, Dees, C, Beyer, C, Daniel, C, Gelse, K, Kremer, AE, Naschberger, E, Stürzl, M, Butter, F, Sticherling, M, Finotto, S, Kreuter, A, Kaplan, MH, Jüngel, A, Gay, S, Nutt, SL, Boykin, DW, Poon, GMK, Distler, O, Schett, G, Distler, JHW, Ramming, A. (2019) PU.1 controls fibroblast polarization and tissue fibrosis. Nature, 566:344-349
  17. Erlitzki, N, Farahat, AA, Kumar, A, Boykin, DW, Poon, GMK. (2019) DNA recognition by linear indole-biphenyl DNA minor groove ligands. Biophys Chem, 245:6-16
  18. Albrecht, AV, Kim, HM, Poon, GMK. (2018) Mapping interfacial hydration in ETS-family transcription factor complexes with DNA: a chimeric approach. Nucleic Acids Res, 46:10577-10588
  19. Mao, P, Brown, AJ, Esaki, S, Lockwood, S, Poon, GMK, Smerdon, MJ, Roberts, SA, Wyrick, JJ. (2018) ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma. Nat Commun, 9:2626
  20. Esaki, S, Evich, MG, Erlitzki, N, Germann, MW, Poon, GMK. (2017) Multiple DNA-binding modes for the ETS family transcription factor PU.1. J Biol Chem, 292:16044-16054
  21. Vo, T, Wang, S, Poon, GMK, Wilson, WD. (2017) Electrostatic control of DNA intersegmental translocation by the ETS transcription factor ETV6. J Biol Chem, 292:13187-13196
  22. Erlitzki, N, Huang, K, Xhani, S, Farahat, AA, Kumar, A, Boykin, DW, Poon, GMK. (2017) Investigation of the electrostatic and hydration properties of DNA minor groove-binding by a heterocyclic diamidine by osmotic pressure. Biophys Chem, 231:95-104
  23. Poon, GMK, Kim, HM. (2017) Signatures of DNA target selectivity by ETS transcription factors. Transcription, 8:193-203
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