- Poon, GMK. (2021) The Non-continuum Nature of Eukaryotic Transcriptional Regulation. Adv Exp Med Biol, :
- Poon, GM, Wong, KL, Chen, H, Saggi, SS, Lai, M, Wong, MK, Chan, D. (2020) Cervical Spine Fracture after a Bone Cracking Traditional (Tui Na) Massage. Ann Acad Med Singap, 49:915-918
- Afek, A, Shi, H, Rangadurai, A, Sahay, H, Senitzki, A, Xhani, S, Fang, M, Salinas, R, Mielko, Z, Pufall, MA, Poon, GMK, Haran, TE, Schumacher, MA, Al-Hashimi, HM, Gordân, R. (2020) DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature, 587:291-296
- Ha, VLT, Erlitzki, N, Farahat, AA, Kumar, A, Boykin, DW, Poon, GMK. (2020) Dissecting Dynamic and Hydration Contributions to Sequence-Dependent DNA Minor Groove Recognition. Biophys J, 119:1402-1415
- Xhani, S, Lee, S, Kim, HM, Wang, S, Esaki, S, Ha, VLT, Khanezarrin, M, Fernandez, GL, Albrecht, AV, Aramini, JM, Germann, MW, Poon, GMK. (2020) Intrinsic disorder controls two functionally distinct dimers of the master transcription factor PU.1. Sci Adv, 6:eaay3178
- Liu, B, Bashkin, JK, Poon, GMK, Wang, S, Wang, S, Wilson, WD. (2019) Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions. Biochimie, 167:1-11
- Vo, T, Albrecht, AV, Wilson, WD, Poon, GMK. (2019) Quantifying length-dependent DNA end-binding by nucleoproteins. Biophys Chem, 251:106177
- Huang, K, Xhani, S, Albrecht, AV, Ha, VLT, Esaki, S, Poon, GMK. (2019) Mechanism of cognate sequence discrimination by the ETS-family transcription factor ETS-1. J Biol Chem, 294:9666-9678
- Wohlfahrt, T, Rauber, S, Uebe, S, Luber, M, Soare, A, Ekici, A, Weber, S, Matei, AE, Chen, CW, Maier, C, Karouzakis, E, Kiener, HP, Pachera, E, Dees, C, Beyer, C, Daniel, C, Gelse, K, Kremer, AE, Naschberger, E, Stürzl, M, Butter, F, Sticherling, M, Finotto, S, Kreuter, A, Kaplan, MH, Jüngel, A, Gay, S, Nutt, SL, Boykin, DW, Poon, GMK, Distler, O, Schett, G, Distler, JHW, Ramming, A. (2019) PU.1 controls fibroblast polarization and tissue fibrosis. Nature, 566:344-349
- Erlitzki, N, Farahat, AA, Kumar, A, Boykin, DW, Poon, GMK. (2019) DNA recognition by linear indole-biphenyl DNA minor groove ligands. Biophys Chem, 245:6-16
- Albrecht, AV, Kim, HM, Poon, GMK. (2018) Mapping interfacial hydration in ETS-family transcription factor complexes with DNA: a chimeric approach. Nucleic Acids Res, 46:10577-10588
- Mao, P, Brown, AJ, Esaki, S, Lockwood, S, Poon, GMK, Smerdon, MJ, Roberts, SA, Wyrick, JJ. (2018) ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma. Nat Commun, 9:2626
- Antony-Debré, I, Paul, A, Leite, J, Mitchell, K, Kim, HM, Carvajal, LA, Todorova, TI, Huang, K, Kumar, A, Farahat, AA, Bartholdy, B, Narayanagari, SR, Chen, J, Ambesi-Impiombato, A, Ferrando, AA, Mantzaris, I, Gavathiotis, E, Verma, A, Will, B, Boykin, DW, Wilson, WD, Poon, GM, Steidl, U. (2017) Pharmacological inhibition of the transcription factor PU.1 in leukemia. J Clin Invest, 127:4297-4313
- Esaki, S, Evich, MG, Erlitzki, N, Germann, MW, Poon, GMK. (2017) Multiple DNA-binding modes for the ETS family transcription factor PU.1. J Biol Chem, 292:16044-16054
- Vo, T, Wang, S, Poon, GMK, Wilson, WD. (2017) Electrostatic control of DNA intersegmental translocation by the ETS transcription factor ETV6. J Biol Chem, 292:13187-13196
- Erlitzki, N, Huang, K, Xhani, S, Farahat, AA, Kumar, A, Boykin, DW, Poon, GMK. (2017) Investigation of the electrostatic and hydration properties of DNA minor groove-binding by a heterocyclic diamidine by osmotic pressure. Biophys Chem, 231:95-104
- Poon, GMK, Kim, HM. (2017) Signatures of DNA target selectivity by ETS transcription factors. Transcription, 8:193-203
- Xhani, S, Esaki, S, Huang, K, Erlitzki, N, Poon, GM. (2017) Distinct Roles for Interfacial Hydration in Site-Specific DNA Recognition by ETS-Family Transcription Factors. J Phys Chem B, 121:2748-2758
- Stephens, DC, Poon, GM. (2016) Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains. Nucleic Acids Res, 44:8671-8681
- Stephens, DC, Kim, HM, Kumar, A, Farahat, AA, Boykin, DW, Poon, GM. (2016) Pharmacologic efficacy of PU.1 inhibition by heterocyclic dications: a mechanistic analysis. Nucleic Acids Res, 44:4005-13
- Wang, S, Poon, GM, Wilson, WD. (2015) Quantitative Investigation of Protein-Nucleic Acid Interactions by Biosensor Surface Plasmon Resonance. Methods Mol Biol, 1334:313-32
- He, G, Tolic, A, Bashkin, JK, Poon, GM. (2015) Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors. Nucleic Acids Res, 43:4322-31
- Giang, I, Boland, EL, Poon, GM. (2014) Prodrug applications for targeted cancer therapy. AAPS J, 16:899-913
- Wang, S, Linde, MH, Munde, M, Carvalho, VD, Wilson, WD, Poon, GM. (2014) Mechanistic heterogeneity in site recognition by the structurally homologous DNA-binding domains of the ETS family transcription factors Ets-1 and PU.1. J Biol Chem, 289:21605-16
- Boland, EL, Van Dyken, CM, Duckett, RM, McCluskey, AJ, Poon, GM. (2014) Structural complementation of the catalytic domain of pseudomonas exotoxin A. J Mol Biol, 426:645-55
- Munde, M, Wang, S, Kumar, A, Stephens, CE, Farahat, AA, Boykin, DW, Wilson, WD, Poon, GM. (2014) Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines. Nucleic Acids Res, 42:1379-90
- Munde, M, Poon, GM, Wilson, WD. (2013) Probing the electrostatics and pharmacological modulation of sequence-specific binding by the DNA-binding domain of the ETS family transcription factor PU.1: a binding affinity and kinetics investigation. J Mol Biol, 425:1655-69
- Poon, GM. (2013) Quantitative analysis of affinity enhancement by noncovalently oligomeric ligands. Anal Biochem, 433:19-27
- Poon, GM. (2012) DNA binding regulates the self-association of the ETS domain of PU.1 in a sequence-dependent manner. Biochemistry, 51:4096-107
- Poon, GM. (2012) Sequence discrimination by DNA-binding domain of ETS family transcription factor PU.1 is linked to specific hydration of protein-DNA interface. J Biol Chem, 287:18297-307
- Poon, GM. (2010) Explicit formulation of titration models for isothermal titration calorimetry. Anal Biochem, 400:229-36
- McCluskey, AJ, Poon, GM, Bolewska-Pedyczak, E, Srikumar, T, Jeram, SM, Raught, B, Gariépy, J. (2008) The catalytic subunit of shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain. J Mol Biol, 378:375-86
- Poon, GM. (2007) Enhancement of oligomeric stability by covalent linkage and its application to the human p53tet domain: thermodynamics and biological implications. Biochem Soc Trans, 35:1574-8
- McCluskey, AJ, Poon, GM, Gariépy, J. (2007) A rapid and universal tandem-purification strategy for recombinant proteins. Protein Sci, 16:2726-32
- Poon, GM, Gariépy, J. (2007) Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells. Biochem Soc Trans, 35:788-93
- Poon, GM, Brokx, RD, Sung, M, Gariépy, J. (2007) Tandem dimerization of the human p53 tetramerization domain stabilizes a primary dimer intermediate and dramatically enhances its oligomeric stability. J Mol Biol, 365:1217-31
- Sung, M, Poon, GM, Gariépy, J. (2006) The importance of valency in enhancing the import and cell routing potential of protein transduction domain-containing molecules. Biochim Biophys Acta, 1758:355-63
- Poon, GM, Abu-Ghazalah, RM, Macgregor, RB Jr. (2004) Ionic mobilities of duplex and frayed wire DNA in discontinuous buffer electrophoresis: evidence of interactions with amino acids. Biochemistry, 43:16337-47
- Poon, GM, Macgregor, RB Jr. (2004) A thermodynamic basis of DNA sequence selectivity by the ETS domain of murine PU.1. J Mol Biol, 335:113-27
- Macgregor, RB, Poon, GM. (2003) The DNA double helix fifty years on. Comput Biol Chem, 27:461-7
- Poon, GM, Macgregor, RB Jr. (2003) Base coupling in sequence-specific site recognition by the ETS domain of murine PU.1. J Mol Biol, 328:805-19
- Poon, GM, Gross, P, Macgregor, RB Jr. (2002) The sequence-specific association of the ETS domain of murine PU.1 with DNA exhibits unusual energetics. Biochemistry, 41:2361-71